In conversation with Professor David Segal, Field Chief Editor for Frontiers in Genome Editing
Frontiers
NOVEMBER 19, 2021
My first publication, in 1995, showed that making a targeted double-strand break (DSB) in the chromosome could stimulate the DNA repair by approximately 100,000-fold (Maria Jasin has published her landmark study with this same conclusion only a few months earlier). This set off a race to develop tools for making targeted DSBs.
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