The pathologies of heart conditions are complex and interwoven, but they often start with ischaemia.
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The incidence of many heart conditions in wealthy countries is declining. In the United Kingdom, for example, the rates of ischaemic heart disease (IHD), myocardial infarction and heart failure have decreased since 2005. The incidence of atrial fibrillation has increased, probably because of an ageing population.
This article is part of Nature Outlook: Heart health, an editorially independent supplement produced with the financial support of third parties. About this content.